Human normal immunoglobulin is a medicine that contains antibodies (blood proteins which help protect your body against infections).
This medicine is used to prevent certain infections such as:
- hepatitis A (contagious liver infection caused by a virus that is spread through intake of contaminated food or water)
- measles (contagious viral infection characterised by fever, cough, runny nose, watery eyes, white spots inside the cheeks and rashes)
- chickenpox (contagious infection caused by varicella-zoster virus characterised by itchy rash or small fluid-filled blisters)
Human normal immunoglobulin may be used to treat other conditions as decided by your doctor.
Human normal immunoglobulin injection is to be given intramuscularly (into the muscle), usually into the muscles of the upper arm or thigh.
Your doctor or nurse will administer the injection for you.
Do not use Human normal immunoglobulin if you ever had an allergic reaction (e.g. rashes, breathlessness, swollen eyes) to this medicine or any of its ingredients.
Alert your doctor if you have immunoglobulin A or IgA deficiency (a condition wherein the body lacks a sufficient number of immunoglobulin A, a specific blood protein that fights infection) with confirmed antibodies against IgA as Human normal immunoglobulin may not be suitable for you.
Inform your doctor if you have the following conditions:
- high blood pressure
- heart problems
- current or history of blood clotting disorders
- thrombophilic disorders (conditions that increase your tendency to form blood clots)
- problems in blood flow due to thick or viscous blood
- kidney disease
Human normal immunoglobulin is not indicated to be used in individuals who have active symptoms of hepatitis A and for the routine prevention or treatment of chickenpox.
Let your doctor know if you are pregnant or breastfeeding.
Inform your doctor if you have been recently vaccinated. Do not receive any vaccinations without first asking your doctor.
Human normal immunoglobulin may cause any of the following side effects: headache, nausea, tiredness, fever, and pain or swelling at the injection site.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- rashes, breathlessness, swelling of the face, eyes or mouth
- pain, swelling and tenderness in your leg accompanied by redness and warmth
- pain or difficulty in passing urine, change in how much urine is passed, blood in the urine
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Avoid vaccinations with live vaccines during treatment or within 6 months up to 1 year after treatment with Human normal immunoglobulin. Recommendations for the duration of avoiding the vaccination may depend on the type of vaccine. Alert your doctor if you have been recently vaccinated or if you are planning to get vaccinated.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and medicines that you buy without a prescription.
Avoid alcohol.
Store in the refrigerator, between 2-8°C. Do not freeze Human normal immunoglobulin otherwise, it will no longer be effective and should not be used.
If you notice that the injection has changed colour or has become cloudy, do not use it. Throw it away and use a new injection.
Medicines must not be used past the expiry date.
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